Research Areas

Methodology Center researchers conduct methodological research focusing on experimental design and data analysis for the prevention and treatment of problem behaviors, particularly drug abuse and HIV. We apply these new methods in empirical research and disseminate the methods to prevention and treatment scientists.

Uncover Population Profiles

Latent class analysis (LCA) and latent transition analysis (LTA) allow researchers to detect subgroups within a population.

Read more about LCA


Develop Adaptive Interventions

blank SMART diagramJust-in-time adaptive interventions (JITAIs) are a special type of adaptive intervention where—thanks to mobile technology like activity sensors and smartphones—an intervention can be delivered when and where it is needed.

Read more about JITAIs and Related Methods

Optimize Interventions

blank MOST flowchartThe multiphase optimization strategy (MOST) is a framework for engineering efficacious and effective behavioral interventions.

Read more about MOST

Understand Intensive Longitudinal Data

abstract icon of 3 heads with data leaving the mind and entering a computerOur intensive longitudinal data (ILD) project provides tools like the time-varying effect model (TVEM) for analyzing complex data, like smartphone data.

Read more about ILD

Understand Associations That Change Over Time

simulated irregular plot from TVEM macroTime-varying effect modeling (TVEM) allows scientists to understand the way associations between variables change over time.

Read more about TVEM


Identify Important Variables in Large Data Sets

icon of a strand of DNAOur high-dimensional data project provides tools for variable screening and selection in datasets with large numbers of variables, like genetics data.

Read more about high-dimensional data

Prior Research

Missing Data

Casual Inference



Last updated: May 6, 2020