Recommended Readings for Adaptive Interventions

Introduction to adaptive interventions

Collins, L. M., Murphy, S. A., & Bierman, K. A. (2004). A conceptual framework for adaptive preventive interventions. Prevention Science, 5, 185-196.

Murphy, S. A. & McKay, J. R. (2004). Adaptive treatment strategies: An emerging approach for improving treatment effectiveness. Clinical Science (Newsletter of the American Psychological Association Division 12, Section III: The Society for the Science of Clinical Psychology). Winter 2003/Spring 2004.

Murphy, S. A., Lynch, K. G., McKay, J. R., Oslin, D., & TenHave, T. (2007). Developing adaptive treatment strategies in substance abuse research. Drug and Alcohol Dependence, 88(2), S24-S30.

Murphy, S. A. & Almirall, D. (2009). Dynamic treatment regimes. In M. W. Kattan (Ed.), Encyclopedia of medical decision making (pp. 419-422). Thousand Oaks, CA: Sage.

Murphy, S. A., Collins, L. M., & Rush, A. J. (2007). Customizing treatment to the patient: Adaptive treatment strategies (Editorial). Drug and Alcohol Dependence, 88(2), S1-S72.

Introduction to SMART

The first paper in this list is the one we recommend as an initial introduction to SMARTs.

Lei, H., Nahum-Shani, I., Lynch, K., Oslin, D., & Murphy, S. A. (2012). A “SMART” design for building individualized treatment sequences. Annual Review of Clinical Psychology, 8, 14.1 – 14.28.

Nahum-Shani, I., Qian, M., Almirall, D., Pelham, W., Gnagy, B., Fabiano, G., … Murphy, S. A. (2012). Experimental design and primary data analysis methods for comparing adaptive interventions. Psychological Methods, 17, 457-77.

Almirall, D., Nahum-Shani, I., Sherwood, N. E., & Murphy, S. A. (2014), Introduction to SMART designs for the development of adaptive interventions: With application to weight loss research. Translational Behavioral Medicine, 4(3), 260-274.

Murphy, S. A., Lynch, K. G., McKay, J. R., Oslin, D., & TenHave, T. (2007). Developing adaptive treatment strategies in substance abuse research. Drug and Alcohol Dependence, 88(2), S24-S30.

Murphy, S. A., Collins, L. M., & Rush, A. J. (2007). Customizing treatment to the patient: Adaptive treatment strategies (Editorial). Drug and Alcohol Dependence, 88(2), S1-S72.

Almirall, D., Compton, S. N., Gunlicks-Stoessel, M., Duan, N., & Murphy, S. A. (2012). Designing a pilot sequential multiple assignment randomized trial for developing an adaptive treatment strategy. Statistics in Medicine, 31(17), 1887-1902.

Experimental design methods (including SMART)

Oetting, A. I., Levy, J. A., Weiss, R. D. & Murphy, S. A., (2011). Statistical methodology for a SMART design in the development of adaptive treatment strategies. In P.E. Shrout (Ed.), Causality and psychopathology: Finding the determinants of disorders and their cures (pp.179-205). Arlington, VA: American Psychiatric Publishing.

Murphy, S. A., (2005). An experimental design for the development of adaptive treatment strategies. Statistics in Medicine, 24(10), 1455–1481.

Collins, L. M., Nahum-Shani, I., & Almirall, D. (2014). Optimization of behavioral dynamic treatment regimens based on the sequential, multiple assignment, randomized trial (SMART). Clinical Trials, 11, 426-434.

Almirall, D., Lizotte, D., & Murphy, S. (2012). Comment: SMART design issues and the consideration of opposing outcomes: Discussion of “Evaluation of viable dynamic treatment regimes in a sequentially randomized trial of advanced prostate cancer” by Wang, Rotnitzky, Lin, Millikan, and Thall. Journal of the American Statistical Association, 107, 509-512.

Advanced statistical topics (including statistical inference)

Chakraborty, B., & Moodie, E. E. (2013). Statistical methods for dynamic treatment regimes (pp. 31-52). Springer.

Kosorok, M. R., & Moodie, E. E. (2015). Adaptive treatment strategies in practice: Planning trials and analyzing data for personalized medicine. Philadelphia, PA: SIAM.

Murphy, S. A., Van Der Laan, M. J., Robins, J. M., & The Conduct Problems Prevention Research Group (2001). Marginal mean models for dynamic regimes.Journal of the American Statistical Association, 96, 1410-1423.

Laber, E. B., Lizotte, D. J., Qian, M., Pelham, W. E., & Murphy, S. A. (2014). Dynamic treatment regimes: Technical challenges and applications. Electronic Journal of Statistics. 8(1),1225-1272.

Gunter, L., Zhu, J., & Murphy, S. A. (2011). Variable selection for qualitative interactions. Statistical Methodology, 1(8), 42-55.

Chakraborty, B., & Murphy, S. A. (2009). Inference for nonregular parameters in optimal dynamic treatment regimes. Statistical Methods in Medical Research,19(3), 317-343.

Murphy, S. A., & Bingham, D. (2009). Screening experiments for developing dynamic treatment regimes. Journal of the American Statistical Association, 104(458), 391-408.

Data analysis with SMART

Nahum-Shani, I., Qian, M., Almirall, D., Pelham, W., Gnagy, B., Fabiano, G., … Murphy, S. A. (2012). Experimental design and primary data analysis methods for comparing adaptive interventions. Psychological Methods, 17, 457-77.

Nahum-Shani, I., Qian, M., Almirall, D., Pelham, W., Gnagy, B., Fabiano, G., … Murphy, S. A. (2012). Q-learning: A data analysis method for constructing adaptive interventions. Psychological Methods, 17, 478-494.

Shortreed, S. M., Laber, E., Stroup, T. S., Pineau, J., & Murphy, S. A. (2014). A multiple imputation strategy for sequential multiple assignment randomized trials.Statistics in Medicine, 33(24), 4202-14.

Lu, X., Lynch, K. G., Oslin, D. W., & Murphy, S. A. (2015). Comparing treatment policies with assistance from the structural nested mean model.Biometrics. Advance online publication. doi: 10.1111/biom.12391

Ertefaie, A., Wu, T., Lynch, K. G., & Nahum-Shani, I. (2015). Identifying a set that contains the best dynamic treatment regimes. Biostatistics, 17, 135-148.

Chakraborty, B., & Murphy, S. A., (2014). Dynamic treatment regimes. Annual Review of Statistics and its Application, 1, 447-464.

Adaptive interventions and SMART in the field

Gunlicks-Stoessel, M., Mufson, L., Westervelt, A., Almirall, D., & Murphy, S. (2015). A Pilot SMART for developing an adaptive treatment strategy for adolescent depression. Journal of Clinical Child & Adolescent Psychology. Advance online publication. doi:10.1080/15374416.2015.1015133, 1-15.

Kasari, C., Kaiser, A., Goods, K., Nietfeld, J., Mathy, P., Landa, R., murphy, S. A., & Almirall, D. (2014). Communication interventions for minimally verbal children with autism: A sequential multiple assignment randomized trial. Journal of the American Academy of Child and Adolescent Psychiatry. 53(6), 635-46.

August, G. J., Piehler, T. F., & Bloomquist, M. L. (2014). Being “SMART” about adolescent conduct problems prevention: Executing a SMART pilot study in a juvenile diversion agency. Journal of Clinical Child & Adolescent Psychology, 1-15.

Kilbourne, A. M., Almirall, D., Eisenberg, D., Waxmonsky, J., Goodrich, D. E., Fortney, J. C., … Thomas, M. R. (2014). Protocol: Adaptive implementation of effective programs trial (ADEPT): Cluster randomized SMART trial comparing a standard versus enhanced implementation strategy to improve outcomes of a mood disorders program. Implementation Science, 9, 132.

Kilbourne, A. M., Almirall, D., Goodrich, D. E., Lai, Z., Abraham, K. M., Nord, K. M., & Bowersox, N. (2014). Enhancing outreach for persons with serious mental illness: 12-month results from a cluster randomized trial of an adaptive implementation strategy. Implementation Science, 9,(1) 163.